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While antihistamines, like non drowsy antihistamines, work great to block the effects of histamine, you should avoid taking them if you have a metabolic disorder called acute porphyria.

It is also a good idea to avoid them if you have kidney or liver problems or are pregnant.

This is when you experience allergy symptoms, such as sneezing, itchy eyes, wheezing, nasal congestion, and rash.

The most common treatment option includes taking antihistamines to slow down immune system and reduce severity of different symptoms.

They may react with antifungal medicines and antidepressants.

Also, avoid alcohol when you are taking antihistamine because it can make your drowsiness worse.

Avoid first-generation antihistamines if you are suffering from prostate enlargement.

You usually do not experience serious side effects if you take antihistamines to treat allergy.

In this case, your body produces histamines to fight against these substances.

If side effects do happens, the most common ones may include agitation, dizziness, headache, drowsiness, dry mouth, blurred vision, stomach upset, and difficulty passing urine.

Keep in mind that some other medicines can also react with antihistamines and cause certain complications.

Call the local emergency number or 911 if a severe allergic reaction develops.

Besides, it is important to give yourself an epinephrine shot right away if you are carrying an epinephrine auto-injector.

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