Sedating antidepressants sleep

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In spite of the fact that each sedative acts in its own way, they produce beneficial relaxing effect by increasing GABA activity.

At higher doses, it may result in slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes.

The use of these medications can further impede cognitive function for people with dementia, who are also more sensitive to side effects of medications.

Sedatives can sometimes leave the patient with long-term or short-term amnesia.

Doses of sedatives such as benzodiazepines, when used as a hypnotic to induce sleep, tend to be higher than amounts used to relieve anxiety, whereas only low doses are needed to provide a peaceful effect.

Sedatives can be misused to produce an overly-calming effect (alcohol being the classic and most common sedating drug).

The long-term use of benzodiazepines may have a similar effect on the brain as alcohol, and are also implicated in depression, anxiety, posttraumatic stress disorder (PTSD), mania, psychosis, sleep disorders, sexual dysfunction, delirium, and neurocognitive disorders (including benzodiazepine-induced persisting dementia which persists even after the medications are stopped).

Additionally, benzodiazepines can indirectly cause or worsen other psychiatric symptoms (e.g., mood, anxiety, psychosis, irritability) by worsening sleep (i.e., benzodiazepine-induced sleep disorder).

People who have difficulty dealing with stress, anxiety or sleeplessness may overuse or become dependent on sedatives.Like alcohol, benzodiazepines are commonly used to treat insomnia in the short-term (both prescribed and self-medicated), but worsen sleep in the long-term.While benzodiazepines can put people to sleep but, while asleep, the drugs disrupt sleep architecture: decreasing sleep time, delaying time to REM sleep, and decreasing deep slow-wave sleep (the most restorative part of sleep for both energy and mood).Sedatives and alcohol are sometimes combined recreationally or carelessly.Since alcohol is a strong depressant that slows brain function and depresses respiration, the two substances compound each other's actions and this combination can prove fatal.

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